Cargando…

Predictive QSAR model confirms flavonoids in Chinese medicine can activate voltage-gated calcium (CaV) channel in osteogenesis

BACKGROUND: Flavonoids in Chinese Medicine have been proven in animal studies that could aid in osteogenesis and bone formation. However, there is no consented mechanism for how these phytochemicals action on the bone-forming osteoblasts, and henceforth the prediction model of chemical screening for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, Ki, Leung, Henry Chi Ming, Tsoi, James Kit-Hon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106815/ https://www.ncbi.nlm.nih.gov/pubmed/32256687 http://dx.doi.org/10.1186/s13020-020-00313-1

Ejemplares similares

Solution Structure of Kurtoxin: A Gating Modifier Selective for Cav3 Voltage-Gated Ca(2+) Channels
por: Lee, Chul Won, et al.
Publicado: (2012)

Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca(2+) channel function
por: Erdogmus, Serap, et al.
Publicado: (2022)

The voltage‐gated calcium channel CaV1.2 promotes adult oligodendrocyte progenitor cell survival in the mouse corpus callosum but not motor cortex
por: Pitman, Kimberley A., et al.
Publicado: (2019)

CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
por: Mueller, Brian D, et al.
Publicado: (2023)

Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca(V)2.3
por: Gao, Yiwei, et al.
Publicado: (2023)

Structural basis for Ca(2+) selectivity of a voltage-gated calcium channel
por: Tang, Lin, et al.
Publicado: (2013)

Synaptic vesicle capture by CaV2.2 calcium channels
por: Wong, Fiona K., et al.
Publicado: (2013)

BARP suppresses voltage-gated calcium channel activity and Ca(2+)-evoked exocytosis
por: Béguin, Pascal, et al.
Publicado: (2014)

Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (Ca(V)) Channels
por: Ramírez, David, et al.
Publicado: (2017)

Optogenetic Control of Voltage‐Gated Calcium Channels
por: Ma, Guolin, et al.
Publicado: (2018)

Functions of Presynaptic Voltage-gated Calcium Channels
por: Dolphin, Annette C
Publicado: (2020)

RGK regulation of voltage-gated calcium channels
por: Zafir, BURAEI, et al.
Publicado: (2015)

The life cycle of voltage-gated Ca(2+) channels in neurons: an update on the trafficking of neuronal calcium channels
por: Ferron, Laurent, et al.
Publicado: (2021)

Isoprenylated Flavonoids as Ca(v)3.1 Low Voltage-Gated Ca(2+) Channel Inhibitors from Salvia digitaloides
por: Zhao, Jian-Jun, et al.
Publicado: (2021)

Localization of the Activation Gate of a Voltage-gated Ca(2+) Channel
por: Xie, Cheng, et al.
Publicado: (2005)

Correction to: Isoprenylated Flavonoids as Ca(v)3.1 Low Voltage-Gated Ca(2+) Channel Inhibitors from Salvia digitaloides
por: Zhao, Jian-Jun, et al.
Publicado: (2021)

Calmodulin regulation (calmodulation) of voltage-gated calcium channels
por: Ben-Johny, Manu, et al.
Publicado: (2014)

Roles and Regulation of Voltage-gated Calcium Channels in Arrhythmias
por: Kushner, Jared, et al.
Publicado: (2019)

Structural determinants of voltage-gating properties in calcium channels
por: Fernández-Quintero, Monica L, et al.
Publicado: (2021)

Upregulation of Voltage-Gated Calcium Channel Ca(v)1.3 in Bovine Somatotropes Treated with Ghrelin
por: Salinas Zarate, V. M., et al.
Publicado: (2013)

Role of individual S4 segments in gating of Ca(v)3.1 T-type calcium channel by voltage
por: Jurkovicova-Tarabova, Bohumila, et al.
Publicado: (2018)

In vitro and in vivo phosphorylation of the Ca(v)2.3 voltage-gated R-type calcium channel
por: Schneider, T., et al.
Publicado: (2018)

How voltage-gated calcium channels gate forms of homeostatic synaptic plasticity
por: Frank, C. Andrew
Publicado: (2014)

Characterization of two pathological gating-charge substitutions in Cav1.4 L-type calcium channels
por: Heigl, Thomas, et al.
Publicado: (2023)

Calmodulin and Ca(2+) control of voltage gated Na(+) channels
por: Gabelli, Sandra B, et al.
Publicado: (2015)

“Slow” Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA)
por: Zhu, Lei, et al.
Publicado: (2015)

Stabilization of negative activation voltages of Cav1.3 L-Type Ca(2+)-channels by alternative splicing
por: Hofer, Nadja T., et al.
Publicado: (2020)

Mechanistic contribution of CaV3.2 calcium channels to trigeminal neuralgia pathophysiology not clarified
por: Liedtke, Wolfgang
Publicado: (2022)

LRRK2 Regulates Voltage-Gated Calcium Channel Function
por: Bedford, Cade, et al.
Publicado: (2016)

Voltage‐gated calcium channels – from basic mechanisms to disease
por: Striessnig, Jörg
Publicado: (2016)

Voltage-Gated Calcium Channel Antagonists and Traumatic Brain Injury
por: Gurkoff, Gene, et al.
Publicado: (2013)

Voltage-gated calcium channels: Novel targets for cancer therapy
por: Phan, Nam Nhut, et al.
Publicado: (2017)

β subunits of voltage-gated calcium channels in cardiovascular diseases
por: Loh, Kelvin Wei Zhern, et al.
Publicado: (2023)

Disruption of the Key Ca(2+) Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking
por: Meyer, James O., et al.
Publicado: (2019)

Structural Basis of the Modulation of the Voltage‐Gated Calcium Ion Channel Ca(v)1.1 by Dihydropyridine Compounds
por: Gao, Shuai, et al.
Publicado: (2020)

Interactions of Rabconnectin-3 with Cav2 calcium channels
por: Gandini, Maria A., et al.
Publicado: (2019)

STIM1-mediated bidirectional regulation of Ca(2+) entry through voltage-gated calcium channels (VGCC) and calcium-release activated channels (CRAC)
por: Harraz, Osama F., et al.
Publicado: (2014)

Allosteric Voltage Gating of Potassium Channels II: Mslo Channel Gating Charge Movement in the Absence of Ca(2+)
por: Horrigan, Frank T., et al.
Publicado: (1999)

Functional role of voltage gated Ca(2+) channels in heart automaticity
por: Mesirca, Pietro, et al.
Publicado: (2015)

Ca(2+)-dependent modulation of voltage-gated myocyte sodium channels
por: Salvage, Samantha C., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2k9tfh27uvg3nt0v65o5874e72