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OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma
BACKGROUND: OTUB1 (ovarian tumor domain protease domain-containing ubiquitin aldehyde-binding proteins)-mediated deubiquitination of FOXM1 (Forkhead box M1) participates in carcinogenesis of various tumors. We aim to investigate the effect and mechanism of OTUB1/FOXM1 on RCC (renal cell carcinoma) p...
Autores principales: | Zhou, Kai, Mai, Haixing, Zheng, Song, Cai, Weizhong, Yang, Xu, Chen, Zhenlin, Zhan, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106863/ https://www.ncbi.nlm.nih.gov/pubmed/32257108 http://dx.doi.org/10.1186/s13578-020-00408-0 |
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