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Surgery in a Patient with Haemophilia A and Lymphoma
An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106912/ https://www.ncbi.nlm.nih.gov/pubmed/32257466 http://dx.doi.org/10.1155/2020/4852428 |
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author | Cruz, M. S. Santillan, J. Lesser, J. Ortiz, J. Forzani, L. Plaza, P. |
author_facet | Cruz, M. S. Santillan, J. Lesser, J. Ortiz, J. Forzani, L. Plaza, P. |
author_sort | Cruz, M. S. |
collection | PubMed |
description | An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported. Here, we describe the case of a 43-year-old man with severe haemophilia A and a diffuse large B-cell lymphoma, originally diagnosed as a haematoma, who underwent a splenectomy and several associated surgeries as part of his lymphoma treatment. Perioperative treatment with octanate® (human coagulation factor VIII) enabled the successful performance of all surgical interventions required in the context of lymphoma treatment. Nevertheless, differential diagnosis of posttraumatic haematoma in patients with haemophilia should include the consideration of malignancy. |
format | Online Article Text |
id | pubmed-7106912 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-71069122020-04-06 Surgery in a Patient with Haemophilia A and Lymphoma Cruz, M. S. Santillan, J. Lesser, J. Ortiz, J. Forzani, L. Plaza, P. Case Rep Hematol Case Report An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported. Here, we describe the case of a 43-year-old man with severe haemophilia A and a diffuse large B-cell lymphoma, originally diagnosed as a haematoma, who underwent a splenectomy and several associated surgeries as part of his lymphoma treatment. Perioperative treatment with octanate® (human coagulation factor VIII) enabled the successful performance of all surgical interventions required in the context of lymphoma treatment. Nevertheless, differential diagnosis of posttraumatic haematoma in patients with haemophilia should include the consideration of malignancy. Hindawi 2020-03-18 /pmc/articles/PMC7106912/ /pubmed/32257466 http://dx.doi.org/10.1155/2020/4852428 Text en Copyright © 2020 M. S. Cruz et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Cruz, M. S. Santillan, J. Lesser, J. Ortiz, J. Forzani, L. Plaza, P. Surgery in a Patient with Haemophilia A and Lymphoma |
title | Surgery in a Patient with Haemophilia A and Lymphoma |
title_full | Surgery in a Patient with Haemophilia A and Lymphoma |
title_fullStr | Surgery in a Patient with Haemophilia A and Lymphoma |
title_full_unstemmed | Surgery in a Patient with Haemophilia A and Lymphoma |
title_short | Surgery in a Patient with Haemophilia A and Lymphoma |
title_sort | surgery in a patient with haemophilia a and lymphoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106912/ https://www.ncbi.nlm.nih.gov/pubmed/32257466 http://dx.doi.org/10.1155/2020/4852428 |
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