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Surgery in a Patient with Haemophilia A and Lymphoma

An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported....

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Autores principales: Cruz, M. S., Santillan, J., Lesser, J., Ortiz, J., Forzani, L., Plaza, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106912/
https://www.ncbi.nlm.nih.gov/pubmed/32257466
http://dx.doi.org/10.1155/2020/4852428
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author Cruz, M. S.
Santillan, J.
Lesser, J.
Ortiz, J.
Forzani, L.
Plaza, P.
author_facet Cruz, M. S.
Santillan, J.
Lesser, J.
Ortiz, J.
Forzani, L.
Plaza, P.
author_sort Cruz, M. S.
collection PubMed
description An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported. Here, we describe the case of a 43-year-old man with severe haemophilia A and a diffuse large B-cell lymphoma, originally diagnosed as a haematoma, who underwent a splenectomy and several associated surgeries as part of his lymphoma treatment. Perioperative treatment with octanate® (human coagulation factor VIII) enabled the successful performance of all surgical interventions required in the context of lymphoma treatment. Nevertheless, differential diagnosis of posttraumatic haematoma in patients with haemophilia should include the consideration of malignancy.
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spelling pubmed-71069122020-04-06 Surgery in a Patient with Haemophilia A and Lymphoma Cruz, M. S. Santillan, J. Lesser, J. Ortiz, J. Forzani, L. Plaza, P. Case Rep Hematol Case Report An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported. Here, we describe the case of a 43-year-old man with severe haemophilia A and a diffuse large B-cell lymphoma, originally diagnosed as a haematoma, who underwent a splenectomy and several associated surgeries as part of his lymphoma treatment. Perioperative treatment with octanate® (human coagulation factor VIII) enabled the successful performance of all surgical interventions required in the context of lymphoma treatment. Nevertheless, differential diagnosis of posttraumatic haematoma in patients with haemophilia should include the consideration of malignancy. Hindawi 2020-03-18 /pmc/articles/PMC7106912/ /pubmed/32257466 http://dx.doi.org/10.1155/2020/4852428 Text en Copyright © 2020 M. S. Cruz et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cruz, M. S.
Santillan, J.
Lesser, J.
Ortiz, J.
Forzani, L.
Plaza, P.
Surgery in a Patient with Haemophilia A and Lymphoma
title Surgery in a Patient with Haemophilia A and Lymphoma
title_full Surgery in a Patient with Haemophilia A and Lymphoma
title_fullStr Surgery in a Patient with Haemophilia A and Lymphoma
title_full_unstemmed Surgery in a Patient with Haemophilia A and Lymphoma
title_short Surgery in a Patient with Haemophilia A and Lymphoma
title_sort surgery in a patient with haemophilia a and lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106912/
https://www.ncbi.nlm.nih.gov/pubmed/32257466
http://dx.doi.org/10.1155/2020/4852428
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