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miR-210 in Exosomes Derived from Macrophages under High Glucose Promotes Mouse Diabetic Obesity Pathogenesis by Suppressing NDUFA4 Expression

OBJECTIVE: Type 2 diabetes mellitus (T2DM) is featured by insulin resistance and lipid metabolism dysregulation. A large number of miRNAs were identified in exosomes derived from adipose tissue macrophages associated with T2DM pathogenesis, but its pathogenic roles remain unknown. This study is aime...

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Detalles Bibliográficos
Autores principales: Tian, Feng, Tang, Ping, Sun, Zhilian, Zhang, Ruifen, Zhu, Danhua, He, Junying, Liao, Jixing, Wan, Qinghua, Shen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106924/
https://www.ncbi.nlm.nih.gov/pubmed/32258168
http://dx.doi.org/10.1155/2020/6894684