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The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure
OBJECTIVE: To confirm the role of X-ray exposure in treating infected wound fractures at the lower limb and determine X-ray exposure times. METHODS: Fifty-one wound swabs were collected from patients with infected open fractures at the lower limb with grade II, IIIA, B, and C according to the Gustil...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106931/ https://www.ncbi.nlm.nih.gov/pubmed/32256601 http://dx.doi.org/10.1155/2020/3129356 |
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author | Mahdi, Ali A. Al-Salmani, Tuqa S. Al-Qaisi, Mustafa M. |
author_facet | Mahdi, Ali A. Al-Salmani, Tuqa S. Al-Qaisi, Mustafa M. |
author_sort | Mahdi, Ali A. |
collection | PubMed |
description | OBJECTIVE: To confirm the role of X-ray exposure in treating infected wound fractures at the lower limb and determine X-ray exposure times. METHODS: Fifty-one wound swabs were collected from patients with infected open fractures at the lower limb with grade II, IIIA, B, and C according to the Gustilo and Anderson classification system and then cultured. The bacterial isolates were identified by biochemical tests and the VITEK-2 System and tested against several antibiotics. The X-ray exposure was done for open fractures by radiography (at kV133 and 5 milliambers). RESULTS: The higher isolation rate was recorded for Staphylococcus aureus with 21 (41.2%) isolates, and most of them (20, 95.2%) were isolated from grade II fractures. The isolation rate of Gram-negative bacteria was 25.5% for Escherichia coli with 13 isolates, 19.6% for Pseudomonas aeruginosa with 10 isolates, and 13.7% for Klebsiella pneumoniae with 7 isolates, most of which were isolated from grade III fractures. The isolation rate of P. aeruginosa was 60% (6 isolates) from grade IIIA and 71.4% (5 isolates) from grade IIIB for K. pneumoniae, while for E. coli it was 69.2% (9 isolates) from grade IIIC. All the bacterial isolates recorded high levels of antibiotic resistance against most tested antibiotics. Wound cultures of grade II fractures appeared sterile after the first X-ray exposure, and these wounds were infected with S. aureus or P. aeruginosa. However, cultures of grade IIIA and IIIB fractures appeared sterile after the second X-ray exposure for all isolated bacteria, except for S. aureus (grade IIIA fractures) (after the third X-ray exposure). Grade IIIC fractures showed sterile culture after the third X-ray exposure for wounds infected with P. aeruginosa and E. coli. CONCLUSIONS: The study concluded that X-ray exposure showed high effectiveness in treating infected open fractures. |
format | Online Article Text |
id | pubmed-7106931 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-71069312020-04-02 The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure Mahdi, Ali A. Al-Salmani, Tuqa S. Al-Qaisi, Mustafa M. Int J Microbiol Research Article OBJECTIVE: To confirm the role of X-ray exposure in treating infected wound fractures at the lower limb and determine X-ray exposure times. METHODS: Fifty-one wound swabs were collected from patients with infected open fractures at the lower limb with grade II, IIIA, B, and C according to the Gustilo and Anderson classification system and then cultured. The bacterial isolates were identified by biochemical tests and the VITEK-2 System and tested against several antibiotics. The X-ray exposure was done for open fractures by radiography (at kV133 and 5 milliambers). RESULTS: The higher isolation rate was recorded for Staphylococcus aureus with 21 (41.2%) isolates, and most of them (20, 95.2%) were isolated from grade II fractures. The isolation rate of Gram-negative bacteria was 25.5% for Escherichia coli with 13 isolates, 19.6% for Pseudomonas aeruginosa with 10 isolates, and 13.7% for Klebsiella pneumoniae with 7 isolates, most of which were isolated from grade III fractures. The isolation rate of P. aeruginosa was 60% (6 isolates) from grade IIIA and 71.4% (5 isolates) from grade IIIB for K. pneumoniae, while for E. coli it was 69.2% (9 isolates) from grade IIIC. All the bacterial isolates recorded high levels of antibiotic resistance against most tested antibiotics. Wound cultures of grade II fractures appeared sterile after the first X-ray exposure, and these wounds were infected with S. aureus or P. aeruginosa. However, cultures of grade IIIA and IIIB fractures appeared sterile after the second X-ray exposure for all isolated bacteria, except for S. aureus (grade IIIA fractures) (after the third X-ray exposure). Grade IIIC fractures showed sterile culture after the third X-ray exposure for wounds infected with P. aeruginosa and E. coli. CONCLUSIONS: The study concluded that X-ray exposure showed high effectiveness in treating infected open fractures. Hindawi 2020-03-19 /pmc/articles/PMC7106931/ /pubmed/32256601 http://dx.doi.org/10.1155/2020/3129356 Text en Copyright © 2020 Ali A. Mahdi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mahdi, Ali A. Al-Salmani, Tuqa S. Al-Qaisi, Mustafa M. The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure |
title | The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure |
title_full | The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure |
title_fullStr | The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure |
title_full_unstemmed | The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure |
title_short | The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure |
title_sort | novel role of healing from bacterial infections of lower limb open fractures by x-ray exposure |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106931/ https://www.ncbi.nlm.nih.gov/pubmed/32256601 http://dx.doi.org/10.1155/2020/3129356 |
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