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miR‐137 and its target T‐type Ca(V)3.1 channel modulate dedifferentiation and proliferation of cerebrovascular smooth muscle cells in simulated microgravity rats by regulating calcineurin/NFAT pathway

OBJECTIVES: Postflight orthostatic intolerance has been regarded as a major adverse effect after microgravity exposure, in which cerebrovascular adaptation plays a critical role. Our previous finding suggested that dedifferentiation of vascular smooth muscle cells (VSMCs) might be one of the key con...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Chen, Li, Bai, Yun‐Gang, Song, Ji‐Bo, Cheng, Jiu‐Hua, Ma, Hong‐Zhe, Ma, Jin, Xie, Man‐Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106958/
https://www.ncbi.nlm.nih.gov/pubmed/32034930
http://dx.doi.org/10.1111/cpr.12774