Methotrexate Polyglutamation in a Myasthenia Gravis Clinical Trial

INTRODUCTION: Methotrexate (MTX) is an immunosuppressive and anti-inflammatory drug used to treat rheumatoid arthritis (RA) and other autoimmune conditions. MTX is transported into cells, where glutamate moieties are added and is retained as methotrexate polyglutamates (MTXPGs). In the RA literature...

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Detalles Bibliográficos
Autores principales: Pasnoor, Mamatha, Heim, Andrew J., Herbelin, Laura, Statland, Jeffrey, Dimachkie, Mazen M., Becker, Mara, Barohn, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Kansas Medical Center 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106996/
https://www.ncbi.nlm.nih.gov/pubmed/32256969

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