Intranasal Administration of Integrase Defective Lentiviral Vectors Expressing mAbs Protects from H5 Influenza Virus Challenge In Vivo

BACKGROUND: Despite medical advances, we are often unable to rapidly protect non-immune populations from infectious agents. Passive immunotherapy is a fast method of protection, but large-scale administration of monoclonal antibodies (mAbs) in unpractical. The delivery of mAbs using a viral vector c...

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Detalles Bibliográficos
Autores principales: Michelini, Zuleika, Fontana, Judith, Yang, Jianjun, Negri, Donatella, Cara, Andrea, Salvatore, Mirella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7107124/
http://dx.doi.org/10.1093/ofid/ofx163.1355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7107124/
http://dx.doi.org/10.1093/ofid/ofx163.1355

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