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Maintaining the silence: reflections on long-term RNAi

Since the demonstration of RNA interference (RNAi) in mammalian cells, considerable research and financial effort has gone towards implementing RNAi as a viable therapeutic platform. RNAi is, without doubt, the most promising strategy for the treatment of human genetic disorders. Because many of the...

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Detalles Bibliográficos
Autores principales: Raemdonck, Koen, Vandenbroucke, Roosmarijn E., Demeester, Joseph, Sanders, Niek N., De Smedt, Stefaan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108305/
https://www.ncbi.nlm.nih.gov/pubmed/18620073
http://dx.doi.org/10.1016/j.drudis.2008.06.008