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Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri

Ultrasound assisted extraction (UAE) of saikosaponins from Radix Bupleuri (Bupleurum Chinense DC) was studied. The effects of various factors such as time (t), temperature (T), ultrasound power (I), particle size (S), solvent to solid ratio (R) and solvent concentration (C) on the yield of target co...

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Detalles Bibliográficos
Autores principales: Zhao, Shuna, Kwok, Kin-Chor, Liang, Hanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108326/
https://www.ncbi.nlm.nih.gov/pubmed/32288611
http://dx.doi.org/10.1016/j.seppur.2006.12.002
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author Zhao, Shuna
Kwok, Kin-Chor
Liang, Hanhua
author_facet Zhao, Shuna
Kwok, Kin-Chor
Liang, Hanhua
author_sort Zhao, Shuna
collection PubMed
description Ultrasound assisted extraction (UAE) of saikosaponins from Radix Bupleuri (Bupleurum Chinense DC) was studied. The effects of various factors such as time (t), temperature (T), ultrasound power (I), particle size (S), solvent to solid ratio (R) and solvent concentration (C) on the yield of target components were investigated. The experimental results indicated that the extraction by UAE is six times faster than those by conventional thermal extraction. It is also found that fast extraction rate was obtained in the first 30 min of sonication. Prolonged sonication did not give a proportional increase in the yield. For the effect of ultrasound power, the maximum yield was obtained at the power level of around 21 W. Scanning electron microscope (SEM) images of the plant cells after UAE treatment were obtained to provide visual evidence of the sonication effect. The effects of particle size, solvent to solid ratio and solvent concentration on the yield are also discussed. The preliminary optimum conditions for UAE of saikosaponins were found at time of 30 min, temperature of 80 °C, power of 21 W, particle size <0.3 mm, solvent to solid ratio of 25 ml/g and solvent concentration of 50%.
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spelling pubmed-71083262020-03-31 Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri Zhao, Shuna Kwok, Kin-Chor Liang, Hanhua Sep Purif Technol Article Ultrasound assisted extraction (UAE) of saikosaponins from Radix Bupleuri (Bupleurum Chinense DC) was studied. The effects of various factors such as time (t), temperature (T), ultrasound power (I), particle size (S), solvent to solid ratio (R) and solvent concentration (C) on the yield of target components were investigated. The experimental results indicated that the extraction by UAE is six times faster than those by conventional thermal extraction. It is also found that fast extraction rate was obtained in the first 30 min of sonication. Prolonged sonication did not give a proportional increase in the yield. For the effect of ultrasound power, the maximum yield was obtained at the power level of around 21 W. Scanning electron microscope (SEM) images of the plant cells after UAE treatment were obtained to provide visual evidence of the sonication effect. The effects of particle size, solvent to solid ratio and solvent concentration on the yield are also discussed. The preliminary optimum conditions for UAE of saikosaponins were found at time of 30 min, temperature of 80 °C, power of 21 W, particle size <0.3 mm, solvent to solid ratio of 25 ml/g and solvent concentration of 50%. Elsevier B.V. 2007-07-01 2006-12-15 /pmc/articles/PMC7108326/ /pubmed/32288611 http://dx.doi.org/10.1016/j.seppur.2006.12.002 Text en Copyright © 2007 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zhao, Shuna
Kwok, Kin-Chor
Liang, Hanhua
Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
title Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
title_full Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
title_fullStr Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
title_full_unstemmed Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
title_short Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
title_sort investigation on ultrasound assisted extraction of saikosaponins from radix bupleuri
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108326/
https://www.ncbi.nlm.nih.gov/pubmed/32288611
http://dx.doi.org/10.1016/j.seppur.2006.12.002
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