The rational design of vaccines

This review provides an insight into the various opportunities for vaccine intervention, analysis of strategies for vaccine development, vaccine ability to modulate immune responses and resultant rational vaccine design. In addition, wider aspects are considered, such as biotechnological advances, a...

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Detalles Bibliográficos
Autores principales: Bramwell, Vincent W., Perrie, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108399/
https://www.ncbi.nlm.nih.gov/pubmed/16257375
http://dx.doi.org/10.1016/S1359-6446(05)03600-7
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author Bramwell, Vincent W.
Perrie, Yvonne
author_facet Bramwell, Vincent W.
Perrie, Yvonne
author_sort Bramwell, Vincent W.
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description This review provides an insight into the various opportunities for vaccine intervention, analysis of strategies for vaccine development, vaccine ability to modulate immune responses and resultant rational vaccine design. In addition, wider aspects are considered, such as biotechnological advances, advances in immunological understanding and host–pathogen interactions. The key question addressed here is, with all our research and understanding, have we reached a new echelon in vaccine development, that of rational design?
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spelling pubmed-71083992020-03-31 The rational design of vaccines Bramwell, Vincent W. Perrie, Yvonne Drug Discov Today Article This review provides an insight into the various opportunities for vaccine intervention, analysis of strategies for vaccine development, vaccine ability to modulate immune responses and resultant rational vaccine design. In addition, wider aspects are considered, such as biotechnological advances, advances in immunological understanding and host–pathogen interactions. The key question addressed here is, with all our research and understanding, have we reached a new echelon in vaccine development, that of rational design? Elsevier Ltd. 2005-11-15 2005-10-27 /pmc/articles/PMC7108399/ /pubmed/16257375 http://dx.doi.org/10.1016/S1359-6446(05)03600-7 Text en Copyright © 2005 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Bramwell, Vincent W.
Perrie, Yvonne
The rational design of vaccines
title The rational design of vaccines
title_full The rational design of vaccines
title_fullStr The rational design of vaccines
title_full_unstemmed The rational design of vaccines
title_short The rational design of vaccines
title_sort rational design of vaccines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108399/
https://www.ncbi.nlm.nih.gov/pubmed/16257375
http://dx.doi.org/10.1016/S1359-6446(05)03600-7
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