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Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein

Self-binding peptides containing zipper-like sequences, such as the Leu/Ile zipper sequence within the coiled coil regions of proteins and the cross-β spine steric zippers within the amyloid-like fibrils, could bind to the protein-of-origin through homophilic sequence-specific zipper motifs. These s...

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Detalles Bibliográficos
Autores principales: Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108413/
https://www.ncbi.nlm.nih.gov/pubmed/29800727
http://dx.doi.org/10.1016/j.biocel.2018.05.012