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To sense or not to sense viral RNA — essentials of coronavirus innate immune evasion

An essential function of innate immunity is to distinguish self from non-self and receptors have evolved to specifically recognize viral components and initiate the expression of antiviral proteins to restrict viral replication. Coronaviruses are RNA viruses that replicate in the host cytoplasm and...

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Detalles Bibliográficos
Autores principales: Kindler, Eveline, Thiel, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108419/
https://www.ncbi.nlm.nih.gov/pubmed/24908561
http://dx.doi.org/10.1016/j.mib.2014.05.005