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Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

The human positive coactivator 4 (PC4) was originally identified as a multi-functional cofactor capable of mediating transcription activation by diverse gene- and tissue-specific activators. Recent studies suggest that PC4 might also function as a novel cancer biomarker and therapeutic target for di...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Pavlov, Andrei, Malik, Sohail, Chen, Hong, Kim, Nancy, Li, Ziqing, Zhang, Xiaohong, DePamphilis, Melvin L., Roeder, Robert G., Ge, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108703/
https://www.ncbi.nlm.nih.gov/pubmed/32231397
http://dx.doi.org/10.1371/journal.pone.0230670