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Dynamics in the murine norovirus capsid revealed by high-resolution cryo-EM

Icosahedral viral capsids must undergo conformational rearrangements to coordinate essential processes during the viral life cycle. Capturing such conformational flexibility has been technically challenging yet could be key for developing rational therapeutic agents to combat infections. Noroviruses...

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Detalles Bibliográficos
Autores principales: Snowden, Joseph S., Hurdiss, Daniel L., Adeyemi, Oluwapelumi O., Ranson, Neil A., Herod, Morgan R., Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108717/
https://www.ncbi.nlm.nih.gov/pubmed/32231352
http://dx.doi.org/10.1371/journal.pbio.3000649