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A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters
Synthetic sex distorters have recently been developed in the malaria mosquito, relying on endonucleases that target the X-chromosome during spermatogenesis. Although inspired by naturally-occurring traits, it has remained unclear how they function and, given their potential for genetic control, how...
Autores principales: | Fasulo, Barbara, Meccariello, Angela, Morgan, Maya, Borufka, Carl, Papathanos, Philippos Aris, Windbichler, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108745/ https://www.ncbi.nlm.nih.gov/pubmed/32168334 http://dx.doi.org/10.1371/journal.pgen.1008647 |
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