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Self‐organized criticality in human epidemiology
As opposed to most sociological fields, data are available in good quality for human epidemiology, describing the interaction between individuals being susceptible to or infected by a disease. Mathematically, the modelling of such systems is done on the level of stochastic master equations, giving l...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Institute of Physics
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108766/ https://www.ncbi.nlm.nih.gov/pubmed/32255878 http://dx.doi.org/10.1063/1.2008613 |
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author | Stollenwerk, Nico |
author_facet | Stollenwerk, Nico |
author_sort | Stollenwerk, Nico |
collection | PubMed |
description | As opposed to most sociological fields, data are available in good quality for human epidemiology, describing the interaction between individuals being susceptible to or infected by a disease. Mathematically, the modelling of such systems is done on the level of stochastic master equations, giving likelihood functions for real live data. We show in a case study of meningococcal disease, that the observed large fluctuations of outbreaks of disease among the human population can be explained by the theory of accidental pathogens, leading the system towards a critical state, characterized by power laws in outbreak distributions. In order to make the extremely difficult parameter estimation close to a critical state with absorbing boundary possible, we investigate new algorithms for simulation of the disease dynamics on the basis of winner takes all strategies, and combine them with previously developed parameter estimation schemes. |
format | Online Article Text |
id | pubmed-7108766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | American Institute of Physics |
record_format | MEDLINE/PubMed |
spelling | pubmed-71087662020-04-01 Self‐organized criticality in human epidemiology Stollenwerk, Nico AIP Conf Proc Article As opposed to most sociological fields, data are available in good quality for human epidemiology, describing the interaction between individuals being susceptible to or infected by a disease. Mathematically, the modelling of such systems is done on the level of stochastic master equations, giving likelihood functions for real live data. We show in a case study of meningococcal disease, that the observed large fluctuations of outbreaks of disease among the human population can be explained by the theory of accidental pathogens, leading the system towards a critical state, characterized by power laws in outbreak distributions. In order to make the extremely difficult parameter estimation close to a critical state with absorbing boundary possible, we investigate new algorithms for simulation of the disease dynamics on the basis of winner takes all strategies, and combine them with previously developed parameter estimation schemes. American Institute of Physics 2005-07-20 /pmc/articles/PMC7108766/ /pubmed/32255878 http://dx.doi.org/10.1063/1.2008613 Text en All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Stollenwerk, Nico Self‐organized criticality in human epidemiology |
title | Self‐organized criticality in human epidemiology |
title_full | Self‐organized criticality in human epidemiology |
title_fullStr | Self‐organized criticality in human epidemiology |
title_full_unstemmed | Self‐organized criticality in human epidemiology |
title_short | Self‐organized criticality in human epidemiology |
title_sort | self‐organized criticality in human epidemiology |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108766/ https://www.ncbi.nlm.nih.gov/pubmed/32255878 http://dx.doi.org/10.1063/1.2008613 |
work_keys_str_mv | AT stollenwerknico selforganizedcriticalityinhumanepidemiology |