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A model for HIV/AIDS pandemic with optimal control

Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action incidence function are developed. Stability anal...

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Detalles Bibliográficos
Autores principales: Sule, Amiru, Abdullah, Farah Aini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108779/
https://www.ncbi.nlm.nih.gov/pubmed/32255874
http://dx.doi.org/10.1063/1.4915640
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author Sule, Amiru
Abdullah, Farah Aini
author_facet Sule, Amiru
Abdullah, Farah Aini
author_sort Sule, Amiru
collection PubMed
description Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action incidence function are developed. Stability analysis is carried out. And the disease free equilibrium of the basic model was found to be locally asymptotically stable whenever the threshold parameter (RO) value is less than one, and unstable otherwise. The model is extended by introducing two optimal control strategies namely, CD4 counts and treatment for the infective using optimal control theory. Numerical simulation was carried out in order to illustrate the analytic results.
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spelling pubmed-71087792020-04-01 A model for HIV/AIDS pandemic with optimal control Sule, Amiru Abdullah, Farah Aini AIP Conf Proc Contributed Oral Papers Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action incidence function are developed. Stability analysis is carried out. And the disease free equilibrium of the basic model was found to be locally asymptotically stable whenever the threshold parameter (RO) value is less than one, and unstable otherwise. The model is extended by introducing two optimal control strategies namely, CD4 counts and treatment for the infective using optimal control theory. Numerical simulation was carried out in order to illustrate the analytic results. AIP Publishing LLC 2015-05-15 /pmc/articles/PMC7108779/ /pubmed/32255874 http://dx.doi.org/10.1063/1.4915640 Text en All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).
spellingShingle Contributed Oral Papers
Sule, Amiru
Abdullah, Farah Aini
A model for HIV/AIDS pandemic with optimal control
title A model for HIV/AIDS pandemic with optimal control
title_full A model for HIV/AIDS pandemic with optimal control
title_fullStr A model for HIV/AIDS pandemic with optimal control
title_full_unstemmed A model for HIV/AIDS pandemic with optimal control
title_short A model for HIV/AIDS pandemic with optimal control
title_sort model for hiv/aids pandemic with optimal control
topic Contributed Oral Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108779/
https://www.ncbi.nlm.nih.gov/pubmed/32255874
http://dx.doi.org/10.1063/1.4915640
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