Cargando…

A Single Amino Acid at Position 431 of the PB2 Protein Determines the Virulence of H1N1 Swine Influenza Viruses in Mice

Genetic reassortments occurred continuously among multiple subtypes or genotypes of influenza viruses prevalent in pigs. Of note, some reassortant viruses bearing the internal genes of the 2009 pandemic H1N1 (2009/H1N1) virus sporadically caused human infection, which highlights their potential thre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Chengzhi, Xu, Bangfeng, Wu, Yunpu, Yang, Shiman, Jia, Yunhui, Liang, Wenhua, Yang, Dawei, He, Likun, Zhu, Wenfei, Chen, Yan, Yang, Huanliang, Yu, Benliang, Wang, Dayan, Qiao, Chuanling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108842/ https://www.ncbi.nlm.nih.gov/pubmed/31996432 http://dx.doi.org/10.1128/JVI.01930-19

Ejemplares similares

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs
por: Wang, Zeng, et al.
Publicado: (2017)

Pathobiology of an NS1-Truncated H3N2 Swine Influenza Virus Strain in Pigs
por: Vandoorn, Elien, et al.
Publicado: (2022)

Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice
por: Feng, Xiaoxiao, et al.
Publicado: (2016)

Combinational Deletions of MGF110-9L and MGF505-7R Genes from the African Swine Fever Virus Inhibit TBK1 Degradation by an Autophagy Activator PIK3C2B To Promote Type I Interferon Production
por: Zhu, Guoqiang, et al.
Publicado: (2023)

The African swine fever virus I10L protein inhibits the NF-κB signaling pathway by targeting IKKβ
por: Chen, Xing, et al.
Publicado: (2023)

Differential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection
por: Rathakrishnan, Anusyah, et al.
Publicado: (2022)

Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge
por: Ding, Mingyang, et al.
Publicado: (2022)

The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge
por: Li, Yongfeng, et al.
Publicado: (2022)

African swine fever virus B175L inhibits the type I interferon pathway by targeting STING and 2′3′-cGAMP
por: Ranathunga, Lakmal, et al.
Publicado: (2023)

African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway
por: Dodantenna, Niranjan, et al.
Publicado: (2022)

FMDV 3A Antagonizes the Effect of ANXA1 to Positively Modulate Viral Replication
por: Ma, XuSheng, et al.
Publicado: (2022)

Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge
por: Reis, Ana L., et al.
Publicado: (2017)

Role of African Swine Fever Virus Proteins EP153R and EP402R in Reducing Viral Persistence in Blood and Virulence in Pigs Infected with BeninΔDP148R
por: Petrovan, Vlad, et al.
Publicado: (2022)

Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages
por: Wang, Zhao-Yang, et al.
Publicado: (2020)

Epitope-Containing Short Peptides Capture Distinct IgG Serodynamics That Enable Differentiating Infected from Vaccinated Animals for Live-Attenuated Vaccines
por: Xue, Qinghong, et al.
Publicado: (2020)

Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses
por: Xu, Chengzhi, et al.
Publicado: (2022)

Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1
por: Zhang, Yu, et al.
Publicado: (2020)

Foot-and-Mouth Disease Virus Structural Protein VP1 Destroys the Stability of the TPL2 Trimer by Degradation of TPL2 To Evade Host Antiviral Immunity
por: Zhang, Keshan, et al.
Publicado: (2021)

Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
por: Christensen, Shannon R., et al.
Publicado: (2019)

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1
por: Brown, James R., et al.
Publicado: (2016)

The Omicron Variant BA.1.1 Presents a Lower Pathogenicity than B.1 D614G and Delta Variants in a Feline Model of SARS-CoV-2 Infection
por: Martins, Mathias, et al.
Publicado: (2022)

Establishment of a Cynomolgus Macaque Model of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Direct Inoculation of Adult T-Cell Leukemia Patient-Derived Cell Lines for HTLV-1 Infection
por: Urano, Emiko, et al.
Publicado: (2022)

CD32(+) and PD-1(+) Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals
por: Noto, Alessandra, et al.
Publicado: (2018)

Inefficient HIV-1 trans Infection of CD4(+) T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN
por: DeLucia, Diana C., et al.
Publicado: (2018)

Control of HIV-1 Replication by CD8(+) T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection
por: Nguyen, Hung The, et al.
Publicado: (2022)

Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 Infection
por: Jiang, Rosie T., et al.
Publicado: (2017)

Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies
por: Kuriakose Gift, Syna, et al.
Publicado: (2023)

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
por: Shivkumar, Maitreyi, et al.
Publicado: (2013)

Expression of HIV-1 Intron-Containing RNA in Microglia Induces Inflammatory Responses
por: Akiyama, Hisashi, et al.
Publicado: (2021)

HIV-Infected Macrophages Are Infected and Killed by the Interferon-Sensitive Rhabdovirus MG1
por: Sandstrom, Teslin S., et al.
Publicado: (2021)

Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele
por: Zhang, Yu, et al.
Publicado: (2022)

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1
por: O'Connor, Geraldine M., et al.
Publicado: (2015)

A Highly Unusual V1 Region of Env in an Elite Controller of HIV Infection
por: Silver, Zachary A., et al.
Publicado: (2019)

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA
por: Gaebler, Christian, et al.
Publicado: (2021)

MALT1 Controls Attenuated Rabies Virus by Inducing Early Inflammation and T Cell Activation in the Brain
por: Kip, E., et al.
Publicado: (2018)

Control of HIV-1 Pathogenesis in Viremic Nonprogressors Is Independent of Gag-Specific Cytotoxic T Lymphocyte Responses
por: Salgado, Maria, et al.
Publicado: (2018)

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Primary African Isolates
por: Lorenzi, Julio C. C., et al.
Publicado: (2021)

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention, and Cure
por: Li, Hui, et al.
Publicado: (2021)

Viral and Cellular Factors Leading to the Loss of CD4 Homeostasis in HIV-1 Viremic Nonprogressors
por: Colomer-Lluch, Marta, et al.
Publicado: (2022)

Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation
por: Woodburn, Blaide M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b6m61htud1cd7dkp4c64umjbd2