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Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind
Is vision necessary for the development of the categorical organization of the Ventral Occipito-Temporal Cortex (VOTC)? We used fMRI to characterize VOTC responses to eight categories presented acoustically in sighted and early blind individuals, and visually in a separate sighted group. We observed...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108866/ https://www.ncbi.nlm.nih.gov/pubmed/32108572 http://dx.doi.org/10.7554/eLife.50732 |
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author | Mattioni, Stefania Rezk, Mohamed Battal, Ceren Bottini, Roberto Cuculiza Mendoza, Karen E Oosterhof, Nikolaas N Collignon, Olivier |
author_facet | Mattioni, Stefania Rezk, Mohamed Battal, Ceren Bottini, Roberto Cuculiza Mendoza, Karen E Oosterhof, Nikolaas N Collignon, Olivier |
author_sort | Mattioni, Stefania |
collection | PubMed |
description | Is vision necessary for the development of the categorical organization of the Ventral Occipito-Temporal Cortex (VOTC)? We used fMRI to characterize VOTC responses to eight categories presented acoustically in sighted and early blind individuals, and visually in a separate sighted group. We observed that VOTC reliably encodes sound categories in sighted and blind people using a representational structure and connectivity partially similar to the one found in vision. Sound categories were, however, more reliably encoded in the blind than the sighted group, using a representational format closer to the one found in vision. Crucially, VOTC in blind represents the categorical membership of sounds rather than their acoustic features. Our results suggest that sounds trigger categorical responses in the VOTC of congenitally blind and sighted people that partially match the topography and functional profile of the visual response, despite qualitative nuances in the categorical organization of VOTC between modalities and groups. |
format | Online Article Text |
id | pubmed-7108866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-71088662020-04-01 Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind Mattioni, Stefania Rezk, Mohamed Battal, Ceren Bottini, Roberto Cuculiza Mendoza, Karen E Oosterhof, Nikolaas N Collignon, Olivier eLife Neuroscience Is vision necessary for the development of the categorical organization of the Ventral Occipito-Temporal Cortex (VOTC)? We used fMRI to characterize VOTC responses to eight categories presented acoustically in sighted and early blind individuals, and visually in a separate sighted group. We observed that VOTC reliably encodes sound categories in sighted and blind people using a representational structure and connectivity partially similar to the one found in vision. Sound categories were, however, more reliably encoded in the blind than the sighted group, using a representational format closer to the one found in vision. Crucially, VOTC in blind represents the categorical membership of sounds rather than their acoustic features. Our results suggest that sounds trigger categorical responses in the VOTC of congenitally blind and sighted people that partially match the topography and functional profile of the visual response, despite qualitative nuances in the categorical organization of VOTC between modalities and groups. eLife Sciences Publications, Ltd 2020-02-28 /pmc/articles/PMC7108866/ /pubmed/32108572 http://dx.doi.org/10.7554/eLife.50732 Text en © 2020, Mattioni et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Mattioni, Stefania Rezk, Mohamed Battal, Ceren Bottini, Roberto Cuculiza Mendoza, Karen E Oosterhof, Nikolaas N Collignon, Olivier Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
title | Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
title_full | Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
title_fullStr | Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
title_full_unstemmed | Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
title_short | Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
title_sort | categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108866/ https://www.ncbi.nlm.nih.gov/pubmed/32108572 http://dx.doi.org/10.7554/eLife.50732 |
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