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Preliminary In Vivo Safety Evaluation of a Tacrolimus Eye Drop Formulation Using Hydroxypropyl Beta Cyclodextrin After Ocular Administration in NZW Rabbits

AIM: Tacrolimus is an immunosuppressive drug with higher potency compared to cyclosporine A (as a useful immunosuppressant). We prepared an ophthalmic solution formulation of Tacrolimus using hydroxypropyl beta cyclodextrin (HP-ßCD). In the present study, safety of this formulation was investigated...

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Detalles Bibliográficos
Autores principales:	Mahmoudi, Asma, Malaekeh-Nikouei, Bizhan, Hanafi-Bojd, Mohammad Yahya, Toloei, Mojtaba, Hosseini, Mehran, Nikandish, Malihe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108877/ https://www.ncbi.nlm.nih.gov/pubmed/32273679 http://dx.doi.org/10.2147/OPTH.S229405

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