Cargando…

Loss of testosterone impairs anti-tumor neutrophil function

In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent changes in immune cell function account for this eff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Markman, Janet L., Porritt, Rebecca A., Wakita, Daiko, Lane, Malcolm E., Martinon, Daisy, Noval Rivas, Magali, Luu, Michael, Posadas, Edwin M., Crother, Timothy R., Arditi, Moshe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109066/ https://www.ncbi.nlm.nih.gov/pubmed/32235862 http://dx.doi.org/10.1038/s41467-020-15397-4

Ejemplares similares

Notch1 signaling impairs regulatory T cells during multisystem inflammatory syndrome in children
por: Noval Rivas, Magali, et al.
Publicado: (2023)

Platelets exacerbate cardiovascular inflammation in a murine model of Kawasaki disease vasculitis
por: Kocatürk, Begüm, et al.
Publicado: (2023)

COVID-19–associated multisystem inflammatory syndrome in children (MIS-C): A novel disease that mimics toxic shock syndrome—the superantigen hypothesis
por: Noval Rivas, Magali, et al.
Publicado: (2021)

Multisystem Inflammatory Syndrome in Children and Long COVID: The SARS-CoV-2 Viral Superantigen Hypothesis
por: Noval Rivas, Magali, et al.
Publicado: (2022)

Kawasaki disease: pathophysiology and insights from mouse models
por: Noval Rivas, Magali, et al.
Publicado: (2020)

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: Common Inflammatory Pathways of Two Distinct Diseases
por: Noval Rivas, Magali, et al.
Publicado: (2023)

Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice
por: Chen, Shuang, et al.
Publicado: (2020)

MicroRNA-223 Regulates the Development of Cardiovascular Lesions in LCWE-Induced Murine Kawasaki Disease Vasculitis by Repressing the NLRP3 Inflammasome
por: Maruyama, Daisuke, et al.
Publicado: (2021)

Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury
por: Nosaka, Nobuyuki, et al.
Publicado: (2020)

Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis
por: Domiciano, Talita P., et al.
Publicado: (2017)

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation
por: Cheng, Mary Hongying, et al.
Publicado: (2020)

Mitochondrial quality control in health and cardiovascular diseases
por: Atici, Asli E., et al.
Publicado: (2023)

A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
por: Cheng, Mary Hongying, et al.
Publicado: (2020)

A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
por: Cheng, Mary Hongying, et al.
Publicado: (2021)

Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis
por: Marek-Iannucci, Stefanie, et al.
Publicado: (2021)

Characterization of the T Cell Response to Lactobacillus casei Cell Wall Extract in Children With Kawasaki Disease and Its Potential Role in Vascular Inflammation
por: Hsieh, Li-En, et al.
Publicado: (2021)

Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis
por: Porritt, Rebecca A., et al.
Publicado: (2021)

Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection
por: Crother, Timothy R., et al.
Publicado: (2019)

Targeting IRE1 endoribonuclease activity alleviates cardiovascular lesions in a murine model of Kawasaki disease vasculitis
por: Marek-Iannucci, Stefanie, et al.
Publicado: (2022)

IL‐1 receptor antagonist, anakinra, prevents myocardial dysfunction in a mouse model of Kawasaki disease vasculitis and myocarditis
por: Gorelik, M., et al.
Publicado: (2019)

Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
por: Porritt, Rebecca A, et al.
Publicado: (2020)

Nicotinamide Exacerbates Hypoxemia in Ventilator-Induced Lung Injury Independent of Neutrophil Infiltration
por: Jones, Heather D., et al.
Publicado: (2015)

Correction: Nicotinamide Exacerbates Hypoxemia in Ventilator-Induced Lung Injury Independent of Neutrophil Infiltration
por: Jones, Heather D., et al.
Publicado: (2015)

An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations
por: Cheng, Mary Hongying, et al.
Publicado: (2020)

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
por: Tumurkhuu, Gantsetseg, et al.
Publicado: (2020)

Caspase-1 Dependent IL-1β Secretion Is Critical for Host Defense in a Mouse Model of Chlamydia pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2011)

Chlamydia pneumoniae Infection Induced Allergic Airway Sensitization Is Controlled by Regulatory T-Cells and Plasmacytoid Dendritic Cells
por: Crother, Timothy R., et al.
Publicado: (2011)

Plasmacytoid Dendritic Cells Play a Role for Effective Innate Immune Responses during Chlamydia pneumoniae Infection in Mice
por: Crother, Timothy R., et al.
Publicado: (2012)

Chlamydia pneumoniae Infection in Mice Induces Chronic Lung Inflammation, iBALT Formation, and Fibrosis
por: Jupelli, Madhulika, et al.
Publicado: (2013)

Testosterone and weight loss: the evidence
por: Traish, Abdulmaged M.
Publicado: (2014)

Toll-Like Receptor 2 Signaling Protects Mice from Tumor Development in a Mouse Model of Colitis-Induced Cancer
por: Lowe, Emily L., et al.
Publicado: (2010)

Increased Myosin light chain 9 expression during Kawasaki disease vasculitis
por: Kobayashi, Hironobu, et al.
Publicado: (2023)

Platelet-Activating Factor Induces TLR4 Expression in Intestinal Epithelial Cells: Implication for the Pathogenesis of Necrotizing Enterocolitis
por: Soliman, Antoine, et al.
Publicado: (2010)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
por: Shimada, Kenichi, et al.
Publicado: (2009)

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens
por: Brodin, Petter, et al.
Publicado: (2022)

Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies
por: Iwai, Toshiki, et al.
Publicado: (2018)

Time for international action on treating testosterone deficiency syndrome
por: Carruthers, Malcolm
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_tv41v9b785ro0qbttnn74uqii9