Cargando…

Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma

Primary effusion lymphoma (PEL) is a subtype of non-Hodgkin lymphoma associated with infection by Kaposi sarcoma-associated herpes virus (KSHV). PEL is an aggressive disease with extremely poor prognosis when treated with conventional chemotherapy. Narciclasine, a natural product present in Amarylli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gopalakrishnan, Ramakrishnan, Matta, Hittu, Choi, Sunju, Chaudhary, Preet M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109099/ https://www.ncbi.nlm.nih.gov/pubmed/32235878 http://dx.doi.org/10.1038/s41598-020-62690-9

Ejemplares similares

Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors
por: Tolani, Bhairavi, et al.
Publicado: (2013)

Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors
por: Gopalakrishnan, Ramakrishnan, et al.
Publicado: (2015)

A Computational Profiling of Changes in Gene Expression and Transcription Factors Induced by vFLIP K13 in Primary Effusion Lymphoma
por: Punj, Vasu, et al.
Publicado: (2012)

A novel thermostable beetle luciferase based cytotoxicity assay
por: Choi, Sunju, et al.
Publicado: (2021)

A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors
por: Natarajan, Venkatesh, et al.
Publicado: (2020)

Kaposi’s Sarcoma Associated Herpesvirus Encoded Viral FLICE Inhibitory Protein K13 Activates NF-κB Pathway Independent of TRAF6, TAK1 and LUBAC
por: Matta, Hittu, et al.
Publicado: (2012)

Kaposi's sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-κB pathway and functionally cooperates with Tat
por: Sun, Qinmiao, et al.
Publicado: (2005)

Development and characterization of a novel luciferase based cytotoxicity assay
por: Matta, Hittu, et al.
Publicado: (2018)

Integrated microarray and multiplex cytokine analyses of Kaposi's Sarcoma Associated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells
por: Punj, Vasu, et al.
Publicado: (2009)

Conversion of Natural Narciclasine to Its C-1 and C-6 Derivatives and Their Antitumor Activity Evaluation: Some Unusual Chemistry of Narciclasine †
por: Goulart Stollmaier, Juana, et al.
Publicado: (2022)

Narciclasine attenuates sepsis-induced myocardial injury by modulating autophagy
por: Tang, Rong, et al.
Publicado: (2021)

Kaposi's sarcoma associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a
por: Punj, Vasu, et al.
Publicado: (2009)

Concentration-dependent effects of narciclasine on cell cycle progression in Arabidopsis root tips
por: Na, Xiaofan, et al.
Publicado: (2011)

Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle
por: Julien, Sofi G., et al.
Publicado: (2017)

Design and Synthesis of C-1 Methoxycarbonyl Derivative of Narciclasine and Its Biological Activity
por: Habaz, Lihi, et al.
Publicado: (2022)

Narciclasine, a novel topoisomerase I inhibitor, exhibited potent anti-cancer activity against cancer cells
por: Wang, Meichen, et al.
Publicado: (2023)

Narciclasine targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells
por: Lv, Chao, et al.
Publicado: (2022)

Narciclasine inhibits phospholipase A2 and regulates phospholipid metabolism to ameliorate psoriasis-like dermatitis
por: Kong, Yi, et al.
Publicado: (2023)

Narciclasine improves outcome in sepsis among neonatal rats via inhibition of calprotectin and alleviating inflammatory responses
por: Kingsley, Manoj Kumar, et al.
Publicado: (2020)

Where has the lymphoma gone? Pericardial effusion adenosine deaminase may play a key role in diagnosing primary effusion lymphoma-like lymphoma: a case report
por: Fujimoto, Yuhna, et al.
Publicado: (2023)

Current Concepts in Primary Effusion Lymphoma and Other Effusion-Based Lymphomas
por: Kim, Yoonjung, et al.
Publicado: (2014)

Narciclasine induces autophagy-mediated apoptosis in gastric cancer cells through the Akt/mTOR signaling pathway
por: Yuan, Yunfeng, et al.
Publicado: (2021)

Narciclasine attenuates LPS-induced acute lung injury in neonatal rats through suppressing inflammation and oxidative stress
por: Duan, Qingning, et al.
Publicado: (2020)

Primary Effusion Lymphoma Presenting As Parapneumonic Pleural Effusion
por: Gujarathi, Rahul, et al.
Publicado: (2022)

Indolent primary effusion lymphoma
por: Nagrale, Vidya, et al.
Publicado: (2020)

JNK and Macroautophagy Activation by Bortezomib Has a Pro-Survival Effect in Primary Effusion Lymphoma Cells
por: Granato, Marisa, et al.
Publicado: (2013)

Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo
por: Fuchs, Simone, et al.
Publicado: (2015)

Diagnostic significance of adenosine deaminase in pleural effusate for primary effusion lymphoma–like lymphoma
por: Nakako, Soichiro, et al.
Publicado: (2020)

Primary Effusion Lymphoma without an Effusion: A Rare Case of Solid Extracavitary Variant of Primary Effusion Lymphoma in an HIV-Positive Patient
por: Hashmi, Hamza, et al.
Publicado: (2018)

Primary effusion lymphoma: current perspectives
por: Narkhede, Mayur, et al.
Publicado: (2018)

Primary Effusion Lymphoma: A Rare and Challenging Diagnosis for Recurrent Pleural Effusion
por: Pereira, Letícia Jacome, et al.
Publicado: (2023)

A unique case of primary effusion lymphoma‐like lymphoma showing disappearance and recurrence of the body cavity effusion
por: Koeda, Chikahiko, et al.
Publicado: (2017)

Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity
por: Guimarães, Maria A., et al.
Publicado: (2018)

Primary Effusion Lymphoma: A Clinicopathologic Perspective
por: Gathers, Diamone A., et al.
Publicado: (2022)

A novel luciferase-based assay for the detection of Chimeric Antigen Receptors
por: Gopalakrishnan, Ramakrishnan, et al.
Publicado: (2019)

A Case of Human Herpes Virus-8 Unrelated Primary Effusion Lymphoma-Like Lymphoma Presented as Pleural Effusion
por: Kim, Kyung Ho, et al.
Publicado: (2012)

Primary Effusion Lymphoma-like Lymphoma Mimicking Tuberculous Pleural Effusion: Three Case Reports and a Literature Review
por: Hayashino, Kenta, et al.
Publicado: (2022)

Spontaneous regression of dasatinib-related primary effusion lymphoma-like lymphoma
por: Hayashino, Kenta, et al.
Publicado: (2022)

Pleural effusion in Burkitt's lymphoma.
por: Aderele, W. I., et al.
Publicado: (1975)

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future
por: Granato, Marisa, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_18c6o05lbc4h4iphh8lg8ed01r