Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression

BACKGROUND: Perturbation of the major UGT2B17-dependent androgen catabolism pathway has the potential to affect prostate cancer (PCa) progression. The objective was to evaluate UGT2B17 protein expression in primary tumours in relation to hormone levels, disease characteristics and cancer evolution....

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Detalles Bibliográficos
Autores principales: Lévesque, Eric, Labriet, Adrien, Hovington, Hélène, Allain, Éric P., Melo-Garcia, Luciana, Rouleau, Michèle, Brisson, Hervé, Turcotte, Véronique, Caron, Patrick, Villeneuve, Lyne, Leclercq, Mickaël, Droit, Arnaud, Audet-Walsh, Etienne, Simonyan, David, Fradet, Yves, Lacombe, Louis, Guillemette, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109100/
https://www.ncbi.nlm.nih.gov/pubmed/32047296
http://dx.doi.org/10.1038/s41416-020-0749-2

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