Nitric oxide as a source for bacterial triazole biosynthesis

The heterocycle 1,2,3-triazole is among the most versatile chemical scaffolds and has been widely used in diverse fields. However, how nature creates this nitrogen-rich ring system remains unknown. Here, we report the biosynthetic route to the triazole-bearing antimetabolite 8-azaguanine. We reveal...

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Detalles Bibliográficos
Autores principales: Zhao, Guiyun, Guo, Yuan-Yang, Yao, Shunyu, Shi, Xinjie, Lv, Longxian, Du, Yi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109123/
https://www.ncbi.nlm.nih.gov/pubmed/32235841
http://dx.doi.org/10.1038/s41467-020-15420-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109123/
https://www.ncbi.nlm.nih.gov/pubmed/32235841
http://dx.doi.org/10.1038/s41467-020-15420-8

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