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Nitric oxide as a source for bacterial triazole biosynthesis
The heterocycle 1,2,3-triazole is among the most versatile chemical scaffolds and has been widely used in diverse fields. However, how nature creates this nitrogen-rich ring system remains unknown. Here, we report the biosynthetic route to the triazole-bearing antimetabolite 8-azaguanine. We reveal...
Autores principales: | Zhao, Guiyun, Guo, Yuan-Yang, Yao, Shunyu, Shi, Xinjie, Lv, Longxian, Du, Yi-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109123/ https://www.ncbi.nlm.nih.gov/pubmed/32235841 http://dx.doi.org/10.1038/s41467-020-15420-8 |
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