miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells

BACKGROUND: It is important to establish cancer stem cell (CSC)-targeted therapies to eradicate cancer. As it is a CSC marker, we focused on Kruppel-like factor 5 (KLF5) in this study. METHODS: We searched for candidate microRNAs (miRNAs) that inhibited KLF5 expression by in silico analyses and scre...

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Detalles Bibliográficos
Autores principales: Morimoto, Yoshihiro, Mizushima, Tsunekazu, Wu, Xin, Okuzaki, Daisuke, Yokoyama, Yuhki, Inoue, Akira, Hata, Tsuyoshi, Hirose, Haruka, Qian, Yamin, Wang, Jiaqi, Miyoshi, Norikatsu, Takahashi, Hidekazu, Haraguchi, Naotsugu, Matsuda, Chu, Doki, Yuichiro, Mori, Masaki, Yamamoto, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109136/
https://www.ncbi.nlm.nih.gov/pubmed/32066912
http://dx.doi.org/10.1038/s41416-020-0758-1

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