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Hepatocyte‐Specific Expression of Human Carboxylesterase 1 Attenuates Diet‐Induced Steatohepatitis and Hyperlipidemia in Mice

Rodents have at least five carboxylesterase 1 (Ces1) genes, whereas there is only one CES1 gene in humans, raising the question as to whether human CES1 and mouse Ces1 genes share the same functions. In this study, we investigate the role of human CES1 in the development of steatohepatitis or dyslip...

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Detalles Bibliográficos
Autores principales: Xu, Yanyong, Zhu, Yingdong, Bawa, Fathima Cassim, Hu, Shuwei, Pan, Xiaoli, Yin, Liya, Zhang, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109343/
https://www.ncbi.nlm.nih.gov/pubmed/32258948
http://dx.doi.org/10.1002/hep4.1487