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Obesity Reshapes Visceral Fat-Derived MHC I Associated-Immunopeptidomes and Generates Antigenic Peptides to Drive CD8(+) T Cell Responses

Adaptive CD8(+) T cells were observed to contribute to the initiation and progression of obesity-induced visceral adipose tissue (VAT) chronic inflammation that is critically linked to metabolic disorders. Numerous peptides presented by the major histocompatibility complex (MHC) class I molecules at...

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Detalles Bibliográficos
Autores principales:	Chen, Xiaoling, Wang, Shufeng, Huang, Yi, Zhao, Xia, Jia, Xu, Meng, Gang, Zheng, Qian, Zhang, Mengjun, Wu, Yuzhang, Wang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109454/ https://www.ncbi.nlm.nih.gov/pubmed/32217358 http://dx.doi.org/10.1016/j.isci.2020.100977

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