Cargando…
Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice
Nonalcoholic fatty liver disease (NAFLD) is associated with dietary folate deficiency and mutations in genes required for one‑carbon metabolism. However, the mechanism through which this occurs is unclear. To improve our understanding of this link, we investigated liver morphology, metabolism and fu...
Autores principales: | Sowton, Alice P., Padmanabhan, Nisha, Tunster, Simon J., McNally, Ben D., Murgia, Antonio, Yusuf, Aisha, Griffin, Julian L., Murray, Andrew J., Watson, Erica D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109458/ https://www.ncbi.nlm.nih.gov/pubmed/32257815 http://dx.doi.org/10.1016/j.ymgmr.2020.100580 |
Ejemplares similares
-
Metabolic Profiling of the Diabetic Heart: Toward a Richer Picture
por: Sowton, Alice P., et al.
Publicado: (2019) -
The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival
por: Wang, Yu, et al.
Publicado: (2022) -
Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress
por: O’Brien, Katie A., et al.
Publicado: (2021) -
Analysis of MTR and MTRR Polymorphisms for Neural Tube Defects Risk Association
por: Wang, Yongxin, et al.
Publicado: (2015) -
Rapid generation of hypomorphic mutations
por: Arthur, Laura L., et al.
Publicado: (2017)