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A 7-Amino Acid Peptide Mimic from Hepatitis C Virus Hypervariable Region 1 Inhibits Mouse Lung Th9 Cell Differentiation by Blocking CD81 Signaling during Allergic Lung Inflammation

T helper (Th) cells orchestrate allergic lung inflammation in asthma pathogenesis. Th9 is a novel Th cell subset that mainly produces IL-9, a potent proinflammatory cytokine in asthma. A 7-amino acid peptide (7P) of the hypervariable region 1 (HVR1) of hepatitis C virus has been identified as an imp...

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Detalles Bibliográficos
Autores principales: Zhao, Wanzhou, Tan, Conghao, Yu, Xi, Yu, Ruihe, Mei, Qibing, Cheng, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109583/
https://www.ncbi.nlm.nih.gov/pubmed/32258172
http://dx.doi.org/10.1155/2020/4184380

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