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Wild-type IDH2 contributes to Epstein–Barr virus-dependent metabolic alterations and tumorigenesis
OBJECTIVE: Epstein–Barr virus (EBV) is a well-recognized oncogenic virus that can induce host cell metabolic reprogramming and tumorigenesis by targeting vital metabolic enzymes or regulators. This study aims to explore the role of wild-type isocitrate dehydrogenase 2 (IDH2) in metabolic reprogrammi...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109632/ https://www.ncbi.nlm.nih.gov/pubmed/32224436 http://dx.doi.org/10.1016/j.molmet.2020.02.009 |