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Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation

Targeting chemoresistant malignant cells is one of the current major challenges in oncology. Therefore, it is mandatory to refine the characteristics of these cells to monitor their survival and develop adapted therapies. This is of particular interest in acute myeloid leukemia (AML), for which the...

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Detalles Bibliográficos
Autores principales: Boutin, Laetitia, Arnautou, Pierre, Trignol, Aurélie, Ségot, Amandine, Farge, Thomas, Desterke, Christophe, Soave, Sabrina, Clay, Denis, Raffoux, Emmanuel, Sarry, Jean-Emmanuel, Malfuson, Jean-Valère, Lataillade, Jean-Jacques, Le Bousse-Kerdilès, Marie-Caroline, Anginot, Adrienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109715/
https://www.ncbi.nlm.nih.gov/pubmed/31289201
http://dx.doi.org/10.3324/haematol.2018.214379