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Mechanisms of increased mitochondria-dependent necrosis in Wiskott-Aldrich syndrome platelets

Wiskott-Aldrich syndrome (WAS) is associated with thrombocytopenia of unclear origin. We investigated real-time cytosolic calcium dynamics, mitochondrial membrane potential and phoszphatidylserine (PS) exposure in single fibrinogen-bound platelets using confocal microscopy. The WAS platelets had hig...

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Detalles Bibliográficos
Autores principales:	Obydennyi, Sergey I., Artemenko, Elena O., Sveshnikova, Anastasia N., Ignatova, Anastasia A., Varlamova, Tatiana V., Gambaryan, Stepan, Lomakina, Galina Y., Ugarova, Natalia N., Kireev, Igor I., Ataullakhanov, Fazoil I., Novichkova, Galina A., Maschan, Aleksey A., Shcherbina, Anna, Panteleev, Mikhail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109739/ https://www.ncbi.nlm.nih.gov/pubmed/31278208 http://dx.doi.org/10.3324/haematol.2018.214460

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