Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis

Glutathione peroxidase 4 (GPX4) is unique as it is the only enzyme that can prevent detrimental lipid peroxidation in vivo by reducing lipid peroxides to the respective alcohols thereby stabilizing oxidation products of unsaturated fatty acids. During reticulocyte maturation, lipid peroxidation medi...

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Detalles Bibliográficos
Autores principales: Altamura, Sandro, Vegi, Naidu M., Hoppe, Philipp S., Schroeder, Timm, Aichler, Michaela, Walch, Axel, Okreglicka, Katarzyna, Hültner, Lothar, Schneider, Manuela, Ladinig, Camilla, Kuklik-Roos, Cornelia, Mysliwietz, Josef, Janik, Dirk, Neff, Frauke, Rathkolb, Birgit, de Angelis, Mar tin Hrabé, Buske, Christian, da Silva, Ana Rita, Muedder, Katja, Conrad, Marcus, Ganz, Tomas, Kopf, Manfred, Muckenthaler, Martina U., Bornkamm, Georg W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109755/
https://www.ncbi.nlm.nih.gov/pubmed/31248967
http://dx.doi.org/10.3324/haematol.2018.212977

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