Cargando…

Thoracic myelopathy caused by calcification of the ligamentum flavum

Calcification of the ligamentum flavum (CLF), which is a rare disorder that can potentially cause myelopathy, occurs uncommonly in the thoracic spine. Here, we report a rare case of thoracic myelopathy caused by CLF in a 78-year-old man. Magnetic resonance imaging (MRI) showed posterior spinal cord...

Descripción completa

Detalles Bibliográficos
Autores principales: Miura, Kousei, Koda, Masao, Abe, Tetsuya, Funayama, Toru, Noguchi, Hiroshi, Kumagai, Hiroshi, Nagashima, Katsuya, Mataki, Kentaro, Shibao, Yosuke, Yamazaki, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Association of Rural Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110097/
https://www.ncbi.nlm.nih.gov/pubmed/32256869
http://dx.doi.org/10.2185/jrm.2019-018
_version_ 1783513006648328192
author Miura, Kousei
Koda, Masao
Abe, Tetsuya
Funayama, Toru
Noguchi, Hiroshi
Kumagai, Hiroshi
Nagashima, Katsuya
Mataki, Kentaro
Shibao, Yosuke
Yamazaki, Masashi
author_facet Miura, Kousei
Koda, Masao
Abe, Tetsuya
Funayama, Toru
Noguchi, Hiroshi
Kumagai, Hiroshi
Nagashima, Katsuya
Mataki, Kentaro
Shibao, Yosuke
Yamazaki, Masashi
author_sort Miura, Kousei
collection PubMed
description Calcification of the ligamentum flavum (CLF), which is a rare disorder that can potentially cause myelopathy, occurs uncommonly in the thoracic spine. Here, we report a rare case of thoracic myelopathy caused by CLF in a 78-year-old man. Magnetic resonance imaging (MRI) showed posterior spinal cord compression by a hypo-signal intense mass, and computed tomography (CT) revealed CLF and vacuum disc phenomenon at T10/11. After undergoing posterior decompression and instrumented fusion (T9–T12), the patient’s gait difficulties improved. The pathogenesis of CLF is largely unknown; however, it involves accumulation of calcium pyrophosphate dehydrate crystals (CPPD), and CLF from CPPD deposition tends to occur within a thickened and hypertrophic ligament. CLF occurs predominantly in the cervical spine and less frequently in the lumbar spine, with few cases involving the thoraco-lumbar spine. The thoracic spine is characterized by hypomobility; however, the thoraco-lumbar spine has a mobile segment which may potentiate CLF formation. Decompression with fusion surgery can be useful for treating patients with thoraco-lumbar CLF.
format Online
Article
Text
id pubmed-7110097
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Japanese Association of Rural Medicine
record_format MEDLINE/PubMed
spelling pubmed-71100972020-04-06 Thoracic myelopathy caused by calcification of the ligamentum flavum Miura, Kousei Koda, Masao Abe, Tetsuya Funayama, Toru Noguchi, Hiroshi Kumagai, Hiroshi Nagashima, Katsuya Mataki, Kentaro Shibao, Yosuke Yamazaki, Masashi J Rural Med Case Report Calcification of the ligamentum flavum (CLF), which is a rare disorder that can potentially cause myelopathy, occurs uncommonly in the thoracic spine. Here, we report a rare case of thoracic myelopathy caused by CLF in a 78-year-old man. Magnetic resonance imaging (MRI) showed posterior spinal cord compression by a hypo-signal intense mass, and computed tomography (CT) revealed CLF and vacuum disc phenomenon at T10/11. After undergoing posterior decompression and instrumented fusion (T9–T12), the patient’s gait difficulties improved. The pathogenesis of CLF is largely unknown; however, it involves accumulation of calcium pyrophosphate dehydrate crystals (CPPD), and CLF from CPPD deposition tends to occur within a thickened and hypertrophic ligament. CLF occurs predominantly in the cervical spine and less frequently in the lumbar spine, with few cases involving the thoraco-lumbar spine. The thoracic spine is characterized by hypomobility; however, the thoraco-lumbar spine has a mobile segment which may potentiate CLF formation. Decompression with fusion surgery can be useful for treating patients with thoraco-lumbar CLF. The Japanese Association of Rural Medicine 2020-04-01 2020-04 /pmc/articles/PMC7110097/ /pubmed/32256869 http://dx.doi.org/10.2185/jrm.2019-018 Text en ©2020 The Japanese Association of Rural Medicine This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Miura, Kousei
Koda, Masao
Abe, Tetsuya
Funayama, Toru
Noguchi, Hiroshi
Kumagai, Hiroshi
Nagashima, Katsuya
Mataki, Kentaro
Shibao, Yosuke
Yamazaki, Masashi
Thoracic myelopathy caused by calcification of the ligamentum flavum
title Thoracic myelopathy caused by calcification of the ligamentum flavum
title_full Thoracic myelopathy caused by calcification of the ligamentum flavum
title_fullStr Thoracic myelopathy caused by calcification of the ligamentum flavum
title_full_unstemmed Thoracic myelopathy caused by calcification of the ligamentum flavum
title_short Thoracic myelopathy caused by calcification of the ligamentum flavum
title_sort thoracic myelopathy caused by calcification of the ligamentum flavum
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110097/
https://www.ncbi.nlm.nih.gov/pubmed/32256869
http://dx.doi.org/10.2185/jrm.2019-018
work_keys_str_mv AT miurakousei thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT kodamasao thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT abetetsuya thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT funayamatoru thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT noguchihiroshi thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT kumagaihiroshi thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT nagashimakatsuya thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT matakikentaro thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT shibaoyosuke thoracicmyelopathycausedbycalcificationoftheligamentumflavum
AT yamazakimasashi thoracicmyelopathycausedbycalcificationoftheligamentumflavum