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Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review
Schiff bases are versatile organic compounds which are widely used and synthesized by condensation reaction of different amino compound with aldehydes or ketones known as imine. Schiff base ligands are considered as privileged ligands as they are simply synthesized by condensation. They show broad r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110249/ https://www.ncbi.nlm.nih.gov/pubmed/32289101 http://dx.doi.org/10.1016/j.mtchem.2019.100195 |
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author | More, M.S. Joshi, P.G. Mishra, Y.K. Khanna, P.K. |
author_facet | More, M.S. Joshi, P.G. Mishra, Y.K. Khanna, P.K. |
author_sort | More, M.S. |
collection | PubMed |
description | Schiff bases are versatile organic compounds which are widely used and synthesized by condensation reaction of different amino compound with aldehydes or ketones known as imine. Schiff base ligands are considered as privileged ligands as they are simply synthesized by condensation. They show broad range of application in medicine, pharmacy, coordination chemistry, biological activities, industries, food packages, dyes, and polymer and also used as an O(2) detector. Semicarbazone is an imine derivative which is derived from condensation of semicarbazide and suitable aldehyde and ketone. Imine ligand–containing transition metal complexes such as copper, zinc, and cadmium have shown to be excellent precursors for synthesis of metal or metal chalcogenide nanoparticles. In recent years, the researchers have attracted enormous attention toward Schiff bases, semicarbazones, thiosemicarbazones, and their metal complexes owing to numerous applications in pharmacology such as antiviral, antifungal, antimicrobial, antimalarial, antituberculosis, anticancer, anti-HIV, catalytic application in oxidation of organic compounds, and nanotechnology. In this review, we summarize the synthesis, structural, biological, and catalytic application of Schiff bases as well as their metal complexes. |
format | Online Article Text |
id | pubmed-7110249 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71102492020-04-02 Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review More, M.S. Joshi, P.G. Mishra, Y.K. Khanna, P.K. Mater Today Chem Article Schiff bases are versatile organic compounds which are widely used and synthesized by condensation reaction of different amino compound with aldehydes or ketones known as imine. Schiff base ligands are considered as privileged ligands as they are simply synthesized by condensation. They show broad range of application in medicine, pharmacy, coordination chemistry, biological activities, industries, food packages, dyes, and polymer and also used as an O(2) detector. Semicarbazone is an imine derivative which is derived from condensation of semicarbazide and suitable aldehyde and ketone. Imine ligand–containing transition metal complexes such as copper, zinc, and cadmium have shown to be excellent precursors for synthesis of metal or metal chalcogenide nanoparticles. In recent years, the researchers have attracted enormous attention toward Schiff bases, semicarbazones, thiosemicarbazones, and their metal complexes owing to numerous applications in pharmacology such as antiviral, antifungal, antimicrobial, antimalarial, antituberculosis, anticancer, anti-HIV, catalytic application in oxidation of organic compounds, and nanotechnology. In this review, we summarize the synthesis, structural, biological, and catalytic application of Schiff bases as well as their metal complexes. Elsevier Ltd. 2019-12 2019-11-18 /pmc/articles/PMC7110249/ /pubmed/32289101 http://dx.doi.org/10.1016/j.mtchem.2019.100195 Text en © 2019 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article More, M.S. Joshi, P.G. Mishra, Y.K. Khanna, P.K. Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review |
title | Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review |
title_full | Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review |
title_fullStr | Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review |
title_full_unstemmed | Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review |
title_short | Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review |
title_sort | metal complexes driven from schiff bases and semicarbazones for biomedical and allied applications: a review |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110249/ https://www.ncbi.nlm.nih.gov/pubmed/32289101 http://dx.doi.org/10.1016/j.mtchem.2019.100195 |
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