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Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes
All members of the herpesviridae contain within their large tegument protein a cysteine protease module that displays deubiquitinating activity. We report the crystal structure of the cysteine protease domain of murine cytomegalovirus M48 (M48(USP)) in a complex with a ubiquitin (Ub)-based suicide s...
Autores principales: | Schlieker, Christian, Weihofen, Wilhelm A., Frijns, Evelyne, Kattenhorn, Lisa M., Gaudet, Rachelle, Ploegh, Hidde L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110467/ https://www.ncbi.nlm.nih.gov/pubmed/17349955 http://dx.doi.org/10.1016/j.molcel.2007.01.033 |
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