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QM/QM studies for Michael reaction in coronavirus main protease (3CL(Pro))
Severe acute respiratory syndrome (SARS) is an illness caused by a novel corona virus wherein the main proteinase called 3CL(Pro) has been established as a target for drug design. The mechanism of action involves nucleophilic attack by Cys145 present in the active site on the carbonyl carbon of the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110475/ https://www.ncbi.nlm.nih.gov/pubmed/18567519 http://dx.doi.org/10.1016/j.jmgm.2008.05.002 |