Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women

A complete genome sequence of human papillomaviruses (HPV) named as HPV-ujs-21015 was determined by viral metagenomic and PCR methods. The complete genome is 7354 bp in length with GC content of 41.7%, of which the genome was predicted to contain six ORFs (Open Reading Frame, ORF) coding for four ea...

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Autores principales: Ling, Yu, Wang, Jianqiang, Yin, Jun, Xu, Jianpu, Wu, Yufan, Zhou, Rui, Lu, Juan, Yang, Shixing, Wang, Xiaochun, Shen, Quan, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110641/
https://www.ncbi.nlm.nih.gov/pubmed/32234038
http://dx.doi.org/10.1186/s12985-020-01319-9
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author Ling, Yu
Wang, Jianqiang
Yin, Jun
Xu, Jianpu
Wu, Yufan
Zhou, Rui
Lu, Juan
Yang, Shixing
Wang, Xiaochun
Shen, Quan
Zhang, Wen
author_facet Ling, Yu
Wang, Jianqiang
Yin, Jun
Xu, Jianpu
Wu, Yufan
Zhou, Rui
Lu, Juan
Yang, Shixing
Wang, Xiaochun
Shen, Quan
Zhang, Wen
author_sort Ling, Yu
collection PubMed
description A complete genome sequence of human papillomaviruses (HPV) named as HPV-ujs-21015 was determined by viral metagenomic and PCR methods. The complete genome is 7354 bp in length with GC content of 41.7%, of which the genome was predicted to contain six ORFs (Open Reading Frame, ORF) coding for four early proteins (E7, E1, E4, and E2) and two late proteins (L1 and L2). Phylogenetic analysis based on the complete genome and the L1 protein showed that HPV-ujs-21015 belongs to a type 214 member within genus Gamma-6 papillomavirus. It is the first complete genome of Gamma-6 papillomavirus discovered from pregnant women in China.
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spelling pubmed-71106412020-04-07 Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women Ling, Yu Wang, Jianqiang Yin, Jun Xu, Jianpu Wu, Yufan Zhou, Rui Lu, Juan Yang, Shixing Wang, Xiaochun Shen, Quan Zhang, Wen Virol J Short Report A complete genome sequence of human papillomaviruses (HPV) named as HPV-ujs-21015 was determined by viral metagenomic and PCR methods. The complete genome is 7354 bp in length with GC content of 41.7%, of which the genome was predicted to contain six ORFs (Open Reading Frame, ORF) coding for four early proteins (E7, E1, E4, and E2) and two late proteins (L1 and L2). Phylogenetic analysis based on the complete genome and the L1 protein showed that HPV-ujs-21015 belongs to a type 214 member within genus Gamma-6 papillomavirus. It is the first complete genome of Gamma-6 papillomavirus discovered from pregnant women in China. BioMed Central 2020-03-31 /pmc/articles/PMC7110641/ /pubmed/32234038 http://dx.doi.org/10.1186/s12985-020-01319-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Report
Ling, Yu
Wang, Jianqiang
Yin, Jun
Xu, Jianpu
Wu, Yufan
Zhou, Rui
Lu, Juan
Yang, Shixing
Wang, Xiaochun
Shen, Quan
Zhang, Wen
Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
title Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
title_full Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
title_fullStr Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
title_full_unstemmed Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
title_short Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women
title_sort genomic organization of a gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of chinese pregnant women
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110641/
https://www.ncbi.nlm.nih.gov/pubmed/32234038
http://dx.doi.org/10.1186/s12985-020-01319-9
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