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Visualization of protein sequence space with force-directed graphs, and their application to the choice of target-template pairs for homology modelling

The protein sequence-structure gap results from the contrast between rapid, low-cost deep sequencing, and slow, expensive experimental structure determination techniques. Comparative homology modelling may have the potential to close this gap by predicting protein structure in target sequences using...

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Detalles Bibliográficos
Autores principales: Mead, Dylan J.T., Lunagomez, Simón, Gatherer, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110651/
https://www.ncbi.nlm.nih.gov/pubmed/31377535
http://dx.doi.org/10.1016/j.jmgm.2019.07.014