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Visualization of protein sequence space with force-directed graphs, and their application to the choice of target-template pairs for homology modelling
The protein sequence-structure gap results from the contrast between rapid, low-cost deep sequencing, and slow, expensive experimental structure determination techniques. Comparative homology modelling may have the potential to close this gap by predicting protein structure in target sequences using...
Autores principales: | Mead, Dylan J.T., Lunagomez, Simón, Gatherer, Derek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110651/ https://www.ncbi.nlm.nih.gov/pubmed/31377535 http://dx.doi.org/10.1016/j.jmgm.2019.07.014 |
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