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Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study

AIM: To evaluate the contribution of a multiplex PCR for respiratory viruses on antibiotic and antiviral prescription, ancillary test prescription, admission and length of stay of patients. METHODS: Two hundred ninety-one adult and pediatric patients visiting the emergency department during the 2015...

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Autores principales: Busson, L., Bartiaux, M., Brahim, S., Konopnicki, D., Dauby, N., Gérard, M., De Backer, P., Van Vaerenbergh, K., Mahadeb, B., Mekkaoui, L., De Foor, M., Wautier, M., Vandenberg, O., Mols, P., Levy, J., Hallin, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110685/
https://www.ncbi.nlm.nih.gov/pubmed/30926539
http://dx.doi.org/10.1016/j.ijid.2019.03.027
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author Busson, L.
Bartiaux, M.
Brahim, S.
Konopnicki, D.
Dauby, N.
Gérard, M.
De Backer, P.
Van Vaerenbergh, K.
Mahadeb, B.
Mekkaoui, L.
De Foor, M.
Wautier, M.
Vandenberg, O.
Mols, P.
Levy, J.
Hallin, M.
author_facet Busson, L.
Bartiaux, M.
Brahim, S.
Konopnicki, D.
Dauby, N.
Gérard, M.
De Backer, P.
Van Vaerenbergh, K.
Mahadeb, B.
Mekkaoui, L.
De Foor, M.
Wautier, M.
Vandenberg, O.
Mols, P.
Levy, J.
Hallin, M.
author_sort Busson, L.
collection PubMed
description AIM: To evaluate the contribution of a multiplex PCR for respiratory viruses on antibiotic and antiviral prescription, ancillary test prescription, admission and length of stay of patients. METHODS: Two hundred ninety-one adult and pediatric patients visiting the emergency department during the 2015–2016 influenza epidemic were prospectively included and immediately tested 24/7 using the FilmArray Respiratory Panel. The results were communicated to the practitioner in charge as soon as they became available. Clinical and biological data were gathered and analyzed. FINDINGS: Results from the FilmArray Respiratory Panel do not appear to impact admission or antibiotic prescription, with the exception of a lower admission rate for children who tested positive for influenza B. Parameters that account for the clinical decisions evaluated are CRP level, white blood cell count, suspected or proven bacterial infection and, for adult patients only, signs of respiratory distress. Length of stay is also not significantly different between patients with a positive and a negative result. A rapid influenza test result permits a more appropriate prescription of oseltamivir.
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spelling pubmed-71106852020-04-02 Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study Busson, L. Bartiaux, M. Brahim, S. Konopnicki, D. Dauby, N. Gérard, M. De Backer, P. Van Vaerenbergh, K. Mahadeb, B. Mekkaoui, L. De Foor, M. Wautier, M. Vandenberg, O. Mols, P. Levy, J. Hallin, M. Int J Infect Dis Article AIM: To evaluate the contribution of a multiplex PCR for respiratory viruses on antibiotic and antiviral prescription, ancillary test prescription, admission and length of stay of patients. METHODS: Two hundred ninety-one adult and pediatric patients visiting the emergency department during the 2015–2016 influenza epidemic were prospectively included and immediately tested 24/7 using the FilmArray Respiratory Panel. The results were communicated to the practitioner in charge as soon as they became available. Clinical and biological data were gathered and analyzed. FINDINGS: Results from the FilmArray Respiratory Panel do not appear to impact admission or antibiotic prescription, with the exception of a lower admission rate for children who tested positive for influenza B. Parameters that account for the clinical decisions evaluated are CRP level, white blood cell count, suspected or proven bacterial infection and, for adult patients only, signs of respiratory distress. Length of stay is also not significantly different between patients with a positive and a negative result. A rapid influenza test result permits a more appropriate prescription of oseltamivir. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2019-06 2019-03-26 /pmc/articles/PMC7110685/ /pubmed/30926539 http://dx.doi.org/10.1016/j.ijid.2019.03.027 Text en © 2019 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Busson, L.
Bartiaux, M.
Brahim, S.
Konopnicki, D.
Dauby, N.
Gérard, M.
De Backer, P.
Van Vaerenbergh, K.
Mahadeb, B.
Mekkaoui, L.
De Foor, M.
Wautier, M.
Vandenberg, O.
Mols, P.
Levy, J.
Hallin, M.
Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study
title Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study
title_full Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study
title_fullStr Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study
title_full_unstemmed Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study
title_short Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: An interventional study
title_sort contribution of the filmarray respiratory panel in the management of adult and pediatric patients attending the emergency room during 2015–2016 influenza epidemics: an interventional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110685/
https://www.ncbi.nlm.nih.gov/pubmed/30926539
http://dx.doi.org/10.1016/j.ijid.2019.03.027
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