Cargando…
Antitumor activity and biochemical effects of topsentin
Topsentin, a bis(indolyl)imidazole marine natural product, inhibited the proliferation of cultured human and murine tumor cells at micromolar concentrations (ic(50) values ranged from 4 to 40 μM) and was active against in vivo P388 leukemia (%TC = 137, 150 mg/kg, QD1-5) and B16 melanoma (%TC = 144,...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published by Elsevier Inc.
1991
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111053/ https://www.ncbi.nlm.nih.gov/pubmed/1867631 http://dx.doi.org/10.1016/0006-2952(91)90031-Y |