Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes

Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely recover...

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Autores principales: Silva, Rodrigo Otávio Silveira, de Oliveira Júnior, Carlos Augusto, Blanc, Dominique S., Pereira, Silvia Trindade, de Araujo, Mário Cesar Rennó, Vasconcelos, Artur, Lobato, Francisco Carlos Faria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111076/
https://www.ncbi.nlm.nih.gov/pubmed/29621604
http://dx.doi.org/10.1016/j.anaerobe.2018.03.011
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author Silva, Rodrigo Otávio Silveira
de Oliveira Júnior, Carlos Augusto
Blanc, Dominique S.
Pereira, Silvia Trindade
de Araujo, Mário Cesar Rennó
Vasconcelos, Artur
Lobato, Francisco Carlos Faria
author_facet Silva, Rodrigo Otávio Silveira
de Oliveira Júnior, Carlos Augusto
Blanc, Dominique S.
Pereira, Silvia Trindade
de Araujo, Mário Cesar Rennó
Vasconcelos, Artur
Lobato, Francisco Carlos Faria
author_sort Silva, Rodrigo Otávio Silveira
collection PubMed
description Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely recovered after dietary changes. The present work suggests that CDI might occur in dogs with other intestinal alterations. In addition, this report suggests that dysbiosis should be considered in animals that have chronic-recurring diarrhea and test positive for C. difficile.
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spelling pubmed-71110762020-04-02 Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes Silva, Rodrigo Otávio Silveira de Oliveira Júnior, Carlos Augusto Blanc, Dominique S. Pereira, Silvia Trindade de Araujo, Mário Cesar Rennó Vasconcelos, Artur Lobato, Francisco Carlos Faria Anaerobe Article Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely recovered after dietary changes. The present work suggests that CDI might occur in dogs with other intestinal alterations. In addition, this report suggests that dysbiosis should be considered in animals that have chronic-recurring diarrhea and test positive for C. difficile. Elsevier Ltd. 2018-06 2018-04-03 /pmc/articles/PMC7111076/ /pubmed/29621604 http://dx.doi.org/10.1016/j.anaerobe.2018.03.011 Text en © 2018 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Silva, Rodrigo Otávio Silveira
de Oliveira Júnior, Carlos Augusto
Blanc, Dominique S.
Pereira, Silvia Trindade
de Araujo, Mário Cesar Rennó
Vasconcelos, Artur
Lobato, Francisco Carlos Faria
Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
title Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
title_full Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
title_fullStr Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
title_full_unstemmed Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
title_short Clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
title_sort clostridioides difficile infection in dogs with chronic-recurring diarrhea responsive to dietary changes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111076/
https://www.ncbi.nlm.nih.gov/pubmed/29621604
http://dx.doi.org/10.1016/j.anaerobe.2018.03.011
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