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Inhibition of phosphodiesterase suppresses allergic lung inflammation by regulating MCP-1 in an OVA-induced asthma murine model with co-exposure to lipopolysaccharide

OBJECTIVE: Asthma is a chronic inflammatory disease that can lead to severe problems with the respiratory system. This study aimed to evaluate the suppression of allergic airway inflammation of an asthma murine model by 3-isobutyl-1-methylxanthine (IBMX), which is a non-specific cyclic nucleotide ph...

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Detalles Bibliográficos
Autores principales: Lee, Chang Doo, Choi, Won Seok, Choi, Yong Geon, Kang, Hyun Sik, Lee, Wang Tae, Kim, Hong Jo, Lee, Ji-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111082/
https://www.ncbi.nlm.nih.gov/pubmed/32054359
http://dx.doi.org/10.1177/0300060520903663