Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

Severe acute respiratory syndrome (SARS) is caused by a newly emerged coronavirus that infected more than 8000 individuals and resulted in more than 800 fatalities in 2003. Currently, there is no effective treatment for this epidemic. SARS-3CL(pro) has been shown to be essential for replication and...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Yi, King, Ke-Yung, Kuo, Chih-Jung, Fang, Jim-Min, Wu, Ying-Ta, Ho, Ming-Yi, Liao, Chung-Lin, Shie, Jiun-Jie, Liang, Po-Huang, Wong, Chi-Huey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111201/
https://www.ncbi.nlm.nih.gov/pubmed/16638531
http://dx.doi.org/10.1016/j.chembiol.2005.12.008

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