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Coordination of germ layer lineage choice by TET1 during primed pluripotency

Gastrulation in the early postimplantation stage mammalian embryo begins when epiblast cells ingress to form the primitive streak or develop as the embryonic ectoderm. The DNA dioxygenase Tet1 is highly expressed in the epiblast and yet continues to regulate lineage specification during gastrulation...

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Detalles Bibliográficos
Autores principales: Luo, Xinlong, van der Veer, Bernard K., Sun, Lei, Bartoccetti, Michela, Boretto, Matteo, Vankelecom, Hugo, Khoueiry, Rita, Koh, Kian Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111260/
https://www.ncbi.nlm.nih.gov/pubmed/32115407
http://dx.doi.org/10.1101/gad.329474.119

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