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Coordination of germ layer lineage choice by TET1 during primed pluripotency
Gastrulation in the early postimplantation stage mammalian embryo begins when epiblast cells ingress to form the primitive streak or develop as the embryonic ectoderm. The DNA dioxygenase Tet1 is highly expressed in the epiblast and yet continues to regulate lineage specification during gastrulation...
Autores principales: | Luo, Xinlong, van der Veer, Bernard K., Sun, Lei, Bartoccetti, Michela, Boretto, Matteo, Vankelecom, Hugo, Khoueiry, Rita, Koh, Kian Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111260/ https://www.ncbi.nlm.nih.gov/pubmed/32115407 http://dx.doi.org/10.1101/gad.329474.119 |
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