Seneca Valley Virus 3C protease negatively regulates the type I interferon pathway by acting as a viral deubiquitinase

The mechanisms that enable Seneca Valley Virus (SVV) to escape the host innate immune response are not well known. Previous studies demonstrated that SVV 3C(pro) suppresses innate immune responses by cleavage of host proteins and degradation of IRF3 and IRF7 protein expression. Here, we showed that...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Qiao, Liu, Huisheng, Zhu, Zixiang, Yang, Fan, Xue, Qinghong, Cai, Xuepeng, Liu, Xiangtao, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111287/
https://www.ncbi.nlm.nih.gov/pubmed/30408499
http://dx.doi.org/10.1016/j.antiviral.2018.10.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111287/
https://www.ncbi.nlm.nih.gov/pubmed/30408499
http://dx.doi.org/10.1016/j.antiviral.2018.10.028

Ejemplares similares