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Seneca Valley Virus 3C protease negatively regulates the type I interferon pathway by acting as a viral deubiquitinase
The mechanisms that enable Seneca Valley Virus (SVV) to escape the host innate immune response are not well known. Previous studies demonstrated that SVV 3C(pro) suppresses innate immune responses by cleavage of host proteins and degradation of IRF3 and IRF7 protein expression. Here, we showed that...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111287/ https://www.ncbi.nlm.nih.gov/pubmed/30408499 http://dx.doi.org/10.1016/j.antiviral.2018.10.028 |